Nuclear Vav3 is required for polycomb repression complex-1 activity in B-cell lymphoblastic leukemogenesis

Acute B-cell lymphoblastic leukemia (B-ALL) results from oligo-clonal evolution of B-cell progenitors endowed with initiating and propagating leukemia properties. The activation of both the Rac guanine nucleotide exchange factor (Rac GEF) Vav3 and Rac GTPases is required for leukemogenesis mediated...

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Detalles Bibliográficos
Autores principales: Nayak, R. C., Chang, K. H., Singh, A. K., Kotliar, M., Desai, M., Wellendorf, A. M., Wunderlich, M., Bartram, J., Mizukawa, B., Cuadrado, M., Dexheimer, P., Barski, A., Bustelo, X. R., Nassar, N. N., Cancelas, J. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160250/
https://www.ncbi.nlm.nih.gov/pubmed/35650206
http://dx.doi.org/10.1038/s41467-022-30651-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160250/
https://www.ncbi.nlm.nih.gov/pubmed/35650206
http://dx.doi.org/10.1038/s41467-022-30651-7

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