Inhibitory Spike-Timing-Dependent Plasticity Can Account for Pathological Strengthening of Pallido-Subthalamic Synapses in Parkinson’s Disease

Parkinson’s disease (PD) is a neurodegenerative brain disorder associated with dysfunction of the basal ganglia (BG) circuitry. Dopamine (DA) depletion in experimental PD models leads to the pathological strengthening of pallido-subthalamic synaptic connections, contributing to the emergence of abno...

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Detalles Bibliográficos
Autores principales: Madadi Asl, Mojtaba, Asadi , Atefeh, Enayati , Jamil, Valizadeh , Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160312/
https://www.ncbi.nlm.nih.gov/pubmed/35665225
http://dx.doi.org/10.3389/fphys.2022.915626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160312/
https://www.ncbi.nlm.nih.gov/pubmed/35665225
http://dx.doi.org/10.3389/fphys.2022.915626

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