A Drug Combination Rescues Frataxin-Dependent Neural and Cardiac Pathophysiology in FA Models

Friedreich’s ataxia (FA) is an inherited multisystemic neuro- and cardio-degenerative disorder. Seventy-four clinical trials are listed for FA (including past and present), but none are considered FDA/EMA-approved therapy. To date, FA therapeutic strategies have focused along two main lines using a...

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Detalles Bibliográficos
Autores principales: Abeti, Rosella, Jasoliya, Mittal, Al-Mahdawi, Sahar, Pook, Mark, Gonzalez-Robles, Cristina, Hui, Chun Kiu, Cortopassi, Gino, Giunti, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160322/
https://www.ncbi.nlm.nih.gov/pubmed/35664670
http://dx.doi.org/10.3389/fmolb.2022.830650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160322/
https://www.ncbi.nlm.nih.gov/pubmed/35664670
http://dx.doi.org/10.3389/fmolb.2022.830650

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