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An aqueous extract of Khaya senegalensis (Desv.) A. Juss. (Meliaceae) prevents seizures and reduces anxiety in kainate-treated rats: modulation of GABA neurotransmission, oxidative stress, and neuronal loss in the hippocampus

ETHNOPHARMACOLOGICAL RELEVANCE: Temporal lobe epilepsy is the most common form of drug-resistant epilepsy. Therefore, medicinal plants provide an alternative source for the discovery of new antiepileptic drugs. AIM OF THE STUDY: This study was aimed at investigating the antiepileptic- and anxiolytic...

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Detalles Bibliográficos
Autores principales: Kandeda, Antoine Kavaye, Lewale, Stéphanie, Djeuzong, Etienne, Kouamouo, J., Dimo, Théophile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160348/
https://www.ncbi.nlm.nih.gov/pubmed/35663738
http://dx.doi.org/10.1016/j.heliyon.2022.e09549