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An aqueous extract of Khaya senegalensis (Desv.) A. Juss. (Meliaceae) prevents seizures and reduces anxiety in kainate-treated rats: modulation of GABA neurotransmission, oxidative stress, and neuronal loss in the hippocampus
ETHNOPHARMACOLOGICAL RELEVANCE: Temporal lobe epilepsy is the most common form of drug-resistant epilepsy. Therefore, medicinal plants provide an alternative source for the discovery of new antiepileptic drugs. AIM OF THE STUDY: This study was aimed at investigating the antiepileptic- and anxiolytic...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160348/ https://www.ncbi.nlm.nih.gov/pubmed/35663738 http://dx.doi.org/10.1016/j.heliyon.2022.e09549 |