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VDAC1 negatively regulates melanogenesis through the Ca(2+)-calcineurin-CRTC1-MITF pathway

Melanocytes produce melanin for protecting DNA from ultraviolet exposure to maintain genomic stability. However, the precise regulation of melanogenesis is not fully understood. VDAC1, which is mainly localized in the outer mitochondrial membrane, functions as a gatekeeper for the entry or exit of C...

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Detalles Bibliográficos
Autores principales: Wang, Jianli, Gong, Juanjuan, Wang, Qiaochu, Tang, Tieshan, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160443/
https://www.ncbi.nlm.nih.gov/pubmed/35649693
http://dx.doi.org/10.26508/lsa.202101350