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Human Guanylate-Binding Protein 1 Positively Regulates Japanese Encephalitis Virus Replication in an Interferon Gamma Primed Environment

RNA virus infection triggers interferon (IFN) receptor signaling, leading to the activation of hundreds of interferon-stimulated genes (ISGs). Guanylate-binding proteins (GBPs) belong to one such IFN inducible subfamily of guanosine triphosphatases (GTPases) that have been reported to exert broad an...

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Detalles Bibliográficos
Autores principales: Chhabra, Simran, Sharma, Kiran Bala, Kalia, Manjula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160567/
https://www.ncbi.nlm.nih.gov/pubmed/35663470
http://dx.doi.org/10.3389/fcimb.2022.832057