NOX4 Mediates Epithelial Cell Death in Hyperoxic Acute Lung Injury Through Mitochondrial Reactive Oxygen Species

Management of acute respiratory distress involves O(2) supplementation, which is lifesaving, but causes severe hyperoxic acute lung injury (HALI). NADPH oxidase (NOX) could be a major source of reactive oxygen species (ROS) in hyperoxia (HO). Epithelial cell death is a crucial step in the developmen...

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Detalles Bibliográficos
Autores principales: Harijith, Anantha, Basa, Prathima, Ha, Alison, Thomas, Jaya, Jafri, Anjum, Fu, Panfeng, MacFarlane, Peter M., Raffay, Thomas M., Natarajan, Viswanathan, Sudhadevi, Tara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160661/
https://www.ncbi.nlm.nih.gov/pubmed/35662702
http://dx.doi.org/10.3389/fphar.2022.880878

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160661/
https://www.ncbi.nlm.nih.gov/pubmed/35662702
http://dx.doi.org/10.3389/fphar.2022.880878

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