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Comprehensive Mutation Profile in Acute Myeloid Leukemia Patients with RUNX1-RUNX1T1 or CBFB-MYH11 Fusions

OBJECTIVE: This study was undertaken with the aim of better understanding the genomic landscape of core-binding factor (CBF) acute myeloid leukemia (AML). MATERIALS AND METHODS: We retrospectively analyzed 112 genes that were detected using next-generation sequencing in 134 patients with de novo CBF...

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Detalles Bibliográficos
Autores principales: Qin, Wei, Chen, Xiayu, Shen, Hong Jie, Wang, Zheng, Cai, Xiaohui, Jiang, Naike, Hua, Haiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160702/
https://www.ncbi.nlm.nih.gov/pubmed/35445594
http://dx.doi.org/10.4274/tjh.galenos.2022.2021.0641