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The importance of terminal complement inhibition in paroxysmal nocturnal hemoglobinuria

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, chronic hematologic disorder associated with inappropriate terminal complement activity on blood cells that can result in intravascular hemolysis (IVH), thromboembolic events (TEs), and organ damage. Untreated individuals with PNH have an increase...

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Detalles Bibliográficos
Autores principales: Kulasekararaj, Austin G., Brodsky, Robert A., Nishimura, Jun-ichi, Patriquin, Christopher J., Schrezenmeier, Hubert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160915/
https://www.ncbi.nlm.nih.gov/pubmed/35663504
http://dx.doi.org/10.1177/20406207221091046