Sub-Lethal Concentrations of Graphene Oxide Trigger Acute-Phase Response and Impairment of Phase-I Xenobiotic Metabolism in Upcyte(®) Hepatocytes

The impact of graphene oxide on hepatic functional cells represents a crucial evaluation step for its potential application in nanomedicine. Primary human hepatocytes are the gold standard for studying drug toxicity and metabolism; however, current technical limitations may slow down the large-scale...

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Detalles Bibliográficos
Autores principales: Romaldini, A., Spanò, R., Catalano, F., Villa, F., Poggi, A., Sabella, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161028/
https://www.ncbi.nlm.nih.gov/pubmed/35662849
http://dx.doi.org/10.3389/fbioe.2022.867728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161028/
https://www.ncbi.nlm.nih.gov/pubmed/35662849
http://dx.doi.org/10.3389/fbioe.2022.867728

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