Role of tumor infiltrating lymphocytes and spatial immune heterogeneity in sensitivity to PD-1 axis blockers in non-small cell lung cancer

BACKGROUND: Tumor infiltrating lymphocytes (TILs) reflect adaptive antitumor immune responses in cancer and are generally associated with favorable prognosis. However, the relationships between TILs subsets and their spatial arrangement with clinical benefit from immune checkpoint inhibitors (ICI) i...

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Detalles Bibliográficos
Autores principales: Lopez de Rodas, Miguel, Nagineni, Venkata, Ravi, Arvind, Datar, Ila J, Mino-Kenudson, Mari, Corredor, German, Barrera, Cristian, Behlman, Lindsey, Rimm, David L, Herbst, Roy S, Madabhushi, Anant, Riess, Jonathan W, Velcheti, Vamsidhar, Hellmann, Matthew D, Gainor, Justin, Schalper, Kurt A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Immunotherapy Biomarkers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161072/
https://www.ncbi.nlm.nih.gov/pubmed/35649657
http://dx.doi.org/10.1136/jitc-2021-004440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161072/
https://www.ncbi.nlm.nih.gov/pubmed/35649657
http://dx.doi.org/10.1136/jitc-2021-004440

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