Aggressive uveal melanoma displays a high degree of centrosome amplification, opening the door to therapeutic intervention

Uveal melanoma (UM) is the most common intraocular cancer in adults. Whilst treatment of primary UM (PUM) is often successful, around 50% of patients develop metastatic disease with poor outcomes, linked to chromosome 3 loss (monosomy 3, M3). Advances in understanding UM cell biology may indicate ne...

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Detalles Bibliográficos
Autores principales: Sabat‐Pośpiech, Dorota, Fabian‐Kolpanowicz, Kim, Kalirai, Helen, Kipling, Natalie, Coupland, Sarah E, Coulson, Judy M, Fielding, Andrew B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161346/
https://www.ncbi.nlm.nih.gov/pubmed/35474453
http://dx.doi.org/10.1002/cjp2.272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161346/
https://www.ncbi.nlm.nih.gov/pubmed/35474453
http://dx.doi.org/10.1002/cjp2.272

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