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ZBP1-dependent inflammatory cell death, PANoptosis, and cytokine storm disrupt IFN therapeutic efficacy during coronavirus infection

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for coronavirus disease 2019 (COVID-19), continues to cause significant morbidity and mortality in the ongoing global pandemic. Understanding the fundamental mechanisms that govern innate immune and inflammatory resp...

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Detalles Bibliográficos
Autores principales: Karki, Rajendra, Lee, SangJoon, Mall, Raghvendra, Pandian, Nagakannan, Wang, Yaqiu, Sharma, Bhesh Raj, Malireddi, RK Subbarao, Yang, Dong, Trifkovic, Sanja, Steele, Jacob A., Connelly, Jon P., Vishwanath, Gella, Sasikala, Mitnala, Reddy, Duvvur Nageshwar, Vogel, Peter, Pruett-Miller, Shondra M., Webby, Richard, Jonsson, Colleen Beth, Kanneganti, Thirumala-Devi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161373/
https://www.ncbi.nlm.nih.gov/pubmed/35587515
http://dx.doi.org/10.1126/sciimmunol.abo6294