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ZBP1-dependent inflammatory cell death, PANoptosis, and cytokine storm disrupt IFN therapeutic efficacy during coronavirus infection
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for coronavirus disease 2019 (COVID-19), continues to cause significant morbidity and mortality in the ongoing global pandemic. Understanding the fundamental mechanisms that govern innate immune and inflammatory resp...
Autores principales: | Karki, Rajendra, Lee, SangJoon, Mall, Raghvendra, Pandian, Nagakannan, Wang, Yaqiu, Sharma, Bhesh Raj, Malireddi, RK Subbarao, Yang, Dong, Trifkovic, Sanja, Steele, Jacob A., Connelly, Jon P., Vishwanath, Gella, Sasikala, Mitnala, Reddy, Duvvur Nageshwar, Vogel, Peter, Pruett-Miller, Shondra M., Webby, Richard, Jonsson, Colleen Beth, Kanneganti, Thirumala-Devi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161373/ https://www.ncbi.nlm.nih.gov/pubmed/35587515 http://dx.doi.org/10.1126/sciimmunol.abo6294 |
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