Mechanistic Evaluation of the Stability of Arylvinyl-1,2,4-trioxanes under Acidic Conditions for Their Oral Administration as an Antimalarial Drug

[Image: see text] A mechanistic approach to understand the course of metabolism for synthetic 1,2,4-trioxanes, potent antimalarial compounds, to evaluate their bioavailability for antimalarial action has been studied in the present work. It is an important parameter to study the course of metabolism...

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Detalles Bibliográficos
Autores principales: Kumari, Akriti, Karnatak, Manvika, Singh, Ajit Shankar, Hassam, Mohammad, Rawat, Varun, Islam, Mohammad Shahidul, Al-Majid, Abdullah Mohammed, Singh, Mandeep, Verma, Ved Prakash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161402/
https://www.ncbi.nlm.nih.gov/pubmed/35664617
http://dx.doi.org/10.1021/acsomega.2c01321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161402/
https://www.ncbi.nlm.nih.gov/pubmed/35664617
http://dx.doi.org/10.1021/acsomega.2c01321

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