Nintedanib-Containing Dual Conjugates Targeting α(V)β(6) Integrin and Tyrosine Kinase Receptors as Potential Antifibrotic Agents

[Image: see text] α(V)β(6) Integrin plays a fundamental role in the activation of transforming growth factor-β (TGF-β), the major profibrotic mediator; for this reason, α(V)β(6) ligands have recently been forwarded to clinical phases for the therapy of fibrotic diseases. Herein, we report the synthe...

Descripción completa

Detalles Bibliográficos
Autores principales: Bugatti, Kelly, Andreucci, Elena, Monaco, Noemi, Battistini, Lucia, Peppicelli, Silvia, Ruzzolini, Jessica, Curti, Claudio, Zanardi, Franca, Bianchini, Francesca, Sartori, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161413/
https://www.ncbi.nlm.nih.gov/pubmed/35664627
http://dx.doi.org/10.1021/acsomega.2c00535

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161413/
https://www.ncbi.nlm.nih.gov/pubmed/35664627
http://dx.doi.org/10.1021/acsomega.2c00535

Ejemplares similares