Integrative analysis of summary data from GWAS and eQTL studies implicates genes differentially expressed in Alzheimer’s disease

BACKGROUND: Although genome-wide association studies (GWAS) have successfully located various genetic variants susceptible to Alzheimer’s Disease (AD), it is still unclear how specific variants interact with genes and tissues to elucidate pathologies associated with AD. Summary-data-based Mendelian...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Brian, Yao, Xiaohui, Shen, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161451/
https://www.ncbi.nlm.nih.gov/pubmed/35655140
http://dx.doi.org/10.1186/s12864-022-08584-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161451/
https://www.ncbi.nlm.nih.gov/pubmed/35655140
http://dx.doi.org/10.1186/s12864-022-08584-8

Ejemplares similares