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Impaired dynamic interaction of axonal endoplasmic reticulum and ribosomes contributes to defective stimulus–response in spinal muscular atrophy

BACKGROUND: Axonal degeneration and defects in neuromuscular neurotransmission represent a pathological hallmark in spinal muscular atrophy (SMA) and other forms of motoneuron disease. These pathological changes do not only base on altered axonal and presynaptic architecture, but also on alterations...

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Detalles Bibliográficos
Autores principales:	Deng, Chunchu, Reinhard, Sebastian, Hennlein, Luisa, Eilts, Janna, Sachs, Stefan, Doose, Sören, Jablonka, Sibylle, Sauer, Markus, Moradi, Mehri, Sendtner, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161492/ https://www.ncbi.nlm.nih.gov/pubmed/35650592 http://dx.doi.org/10.1186/s40035-022-00304-2

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