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Post-translational modifications on the retinoblastoma protein

The retinoblastoma protein (pRb) functions as a cell cycle regulator controlling G1 to S phase transition and plays critical roles in tumour suppression. It is frequently inactivated in various tumours. The functions of pRb are tightly regulated, where post-translational modifications (PTMs) play cr...

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Detalles Bibliográficos
Autores principales: Zhou, Linbin, Ng, Danny Siu-Chun, Yam, Jason C., Chen, Li Jia, Tham, Clement C., Pang, Chi Pui, Chu, Wai Kit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161509/
https://www.ncbi.nlm.nih.gov/pubmed/35650644
http://dx.doi.org/10.1186/s12929-022-00818-x