BARD1 mystery: tumor suppressors are cancer susceptibility genes

The full-length BRCA1-associated RING domain 1 (BARD1) gene encodes a 777-aa protein. BARD1 displays a dual role in cancer development and progression as it acts as a tumor suppressor and an oncogene. Structurally, BARD1 has homologous domains to BRCA1 that aid their heterodimer interaction to inhib...

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Detalles Bibliográficos
Autores principales: Hawsawi, Yousef M., Shams, Anwar, Theyab, Abdulrahman, Abdali, Wed A., Hussien, Nahed A., Alatwi, Hanan E., Alzahrani, Othman R., Oyouni, Atif Abdulwahab A., Babalghith, Ahmad O., Alreshidi, Mousa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161512/
https://www.ncbi.nlm.nih.gov/pubmed/35650591
http://dx.doi.org/10.1186/s12885-022-09567-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161512/
https://www.ncbi.nlm.nih.gov/pubmed/35650591
http://dx.doi.org/10.1186/s12885-022-09567-4

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