Extracellular vesicle PD-L1 dynamics predict durable response to immune-checkpoint inhibitors and survival in patients with non-small cell lung cancer

BACKGROUND: Immune-checkpoint inhibitors (ICIs) changed the therapeutic landscape of patients with lung cancer. However, only a subset of them derived clinical benefit and evidenced the need to identify reliable predictive biomarkers. Liquid biopsy is the non-invasive and repeatable analysis of biol...

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Detalles Bibliográficos
Autores principales: de Miguel-Perez, Diego, Russo, Alessandro, Arrieta, Oscar, Ak, Murat, Barron, Feliciano, Gunasekaran, Muthukumar, Mamindla, Priyadarshini, Lara-Mejia, Luis, Peterson, Christine B., Er, Mehmet E., Peddagangireddy, Vishal, Buemi, Francesco, Cooper, Brandon, Manca, Paolo, Lapidus, Rena G., Hsia, Ru-Ching, Cardona, Andres F., Naing, Aung, Kaushal, Sunjay, Hirsch, Fred R., Mack, Philip C., Serrano, Maria Jose, Adamo, Vincenzo, Colen, Rivka R., Rolfo, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161571/
https://www.ncbi.nlm.nih.gov/pubmed/35650597
http://dx.doi.org/10.1186/s13046-022-02379-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161571/
https://www.ncbi.nlm.nih.gov/pubmed/35650597
http://dx.doi.org/10.1186/s13046-022-02379-1

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