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Extracellular vesicle PD-L1 dynamics predict durable response to immune-checkpoint inhibitors and survival in patients with non-small cell lung cancer
BACKGROUND: Immune-checkpoint inhibitors (ICIs) changed the therapeutic landscape of patients with lung cancer. However, only a subset of them derived clinical benefit and evidenced the need to identify reliable predictive biomarkers. Liquid biopsy is the non-invasive and repeatable analysis of biol...
Autores principales: | de Miguel-Perez, Diego, Russo, Alessandro, Arrieta, Oscar, Ak, Murat, Barron, Feliciano, Gunasekaran, Muthukumar, Mamindla, Priyadarshini, Lara-Mejia, Luis, Peterson, Christine B., Er, Mehmet E., Peddagangireddy, Vishal, Buemi, Francesco, Cooper, Brandon, Manca, Paolo, Lapidus, Rena G., Hsia, Ru-Ching, Cardona, Andres F., Naing, Aung, Kaushal, Sunjay, Hirsch, Fred R., Mack, Philip C., Serrano, Maria Jose, Adamo, Vincenzo, Colen, Rivka R., Rolfo, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161571/ https://www.ncbi.nlm.nih.gov/pubmed/35650597 http://dx.doi.org/10.1186/s13046-022-02379-1 |
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