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MUC3A promotes the progression of colorectal cancer through the PI3K/Akt/mTOR pathway

Mucin 3A (MUC3A) is overexpressed in colorectal cancer (CRC) and associated with poor prognosis, but the related mechanism remains unclear. Our study found that MUC3A promotes the progression of CRC by activating the PI3K/Akt/mTOR signaling pathway. Knockout of MUC3A significantly inhibited the prol...

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Detalles Bibliográficos
Autores principales: Su, Wei, Feng, Baijie, Hu, Lina, Guo, Xianzhi, Yu, Minghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161576/
https://www.ncbi.nlm.nih.gov/pubmed/35655161
http://dx.doi.org/10.1186/s12885-022-09709-8