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MUC3A promotes the progression of colorectal cancer through the PI3K/Akt/mTOR pathway
Mucin 3A (MUC3A) is overexpressed in colorectal cancer (CRC) and associated with poor prognosis, but the related mechanism remains unclear. Our study found that MUC3A promotes the progression of CRC by activating the PI3K/Akt/mTOR signaling pathway. Knockout of MUC3A significantly inhibited the prol...
Autores principales: | Su, Wei, Feng, Baijie, Hu, Lina, Guo, Xianzhi, Yu, Minghua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161576/ https://www.ncbi.nlm.nih.gov/pubmed/35655161 http://dx.doi.org/10.1186/s12885-022-09709-8 |
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