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A review on the role of PTENP1 in human disorders with an especial focus on tumor suppressor role of this lncRNA

PTENP1 is a long non-coding RNA which has been regarded as a pseudogene of the PTEN tumor suppressor gene. However, it has been shown to be a biologically active transcript that can function as a competing endogenous RNA and enhance expression of PTEN protein. This lncRNA has two transcripts, namely...

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Detalles Bibliográficos
Autores principales: Ghafouri-Fard, Soudeh, Khoshbakht, Tayyebeh, Hussen, Bashdar Mahmud, Taheri, Mohammad, Akbari Dilmaghani, Nader
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161594/
https://www.ncbi.nlm.nih.gov/pubmed/35655204
http://dx.doi.org/10.1186/s12935-022-02625-8