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Using Single Cell Transcriptomics to Elucidate the Myeloid Compartment in Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDAC) is a dismal disease with a 5-year survival rate of 10%. A hallmark feature of this disease is its abundant microenvironment which creates a highly immunosuppressive milieu. This is, in large part, mediated by an abundant infiltration of myeloid cells in the PD...

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Detalles Bibliográficos
Autores principales: Kadiyala, Padma, Elhossiny, Ahmed M., Carpenter, Eileen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161632/
https://www.ncbi.nlm.nih.gov/pubmed/35664793
http://dx.doi.org/10.3389/fonc.2022.881871