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Inhibition of Serine Proteases as a Novel Therapeutic Strategy for Abdominal Pain in IBS
Serine proteases are heavily present in the gastrointestinal tract where they are essential in numerous physiological processes. An imbalance in the proteolytic activity is a central mechanism underlying abdominal pain in irritable bowel syndrome (IBS). Therefore, protease inhibitors are emerging as...
Autores principales: | Decraecker, Lisse, Boeckxstaens, Guy, Denadai-Souza, Alexandre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161638/ https://www.ncbi.nlm.nih.gov/pubmed/35665224 http://dx.doi.org/10.3389/fphys.2022.880422 |
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