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Natural Compounds Tapinarof and Galactomyces Ferment Filtrate Downregulate IL-33 Expression via the AHR/IL-37 Axis in Human Keratinocytes

Interleukin (IL)-37 suppresses systemic and local inflammation. It is expressed in the epidermis, the external layer of the skin, and is decreased in inflammatory skin diseases including atopic dermatitis (AD) and psoriasis. Therefore, an agent applied topically on the skin that can increase IL-37 c...

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Detalles Bibliográficos
Autores principales: Tsuji, Gaku, Hashimoto-Hachiya, Akiko, Matsuda-Taniguchi, Tomoyo, Takai-Yumine, Ayako, Takemura, Masaki, Yan, Xianghong, Furue, Masutaka, Nakahara, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161696/
https://www.ncbi.nlm.nih.gov/pubmed/35663970
http://dx.doi.org/10.3389/fimmu.2022.745997