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Natural Compounds Tapinarof and Galactomyces Ferment Filtrate Downregulate IL-33 Expression via the AHR/IL-37 Axis in Human Keratinocytes
Interleukin (IL)-37 suppresses systemic and local inflammation. It is expressed in the epidermis, the external layer of the skin, and is decreased in inflammatory skin diseases including atopic dermatitis (AD) and psoriasis. Therefore, an agent applied topically on the skin that can increase IL-37 c...
Autores principales: | Tsuji, Gaku, Hashimoto-Hachiya, Akiko, Matsuda-Taniguchi, Tomoyo, Takai-Yumine, Ayako, Takemura, Masaki, Yan, Xianghong, Furue, Masutaka, Nakahara, Takeshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161696/ https://www.ncbi.nlm.nih.gov/pubmed/35663970 http://dx.doi.org/10.3389/fimmu.2022.745997 |
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