Activation and Regulation of NLRP3 by Sterile and Infectious Insults

Nod-Like Receptor (NLR) is the largest family of Pathogen Recognition Receptors (PRRs) that patrols the cytosolic environment. NLR engagement drives caspase-1 activation that cleaves pro-IL-1B which then gets secreted. Released IL-1B recruits immune cells to the site of infection/injury. Caspase-1 a...

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Detalles Bibliográficos
Autores principales: Banerjee, Srijon K., Chatterjee, Ayan, Gupta, Shamba, Nagar, Abhinit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161712/
https://www.ncbi.nlm.nih.gov/pubmed/35663964
http://dx.doi.org/10.3389/fimmu.2022.896353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161712/
https://www.ncbi.nlm.nih.gov/pubmed/35663964
http://dx.doi.org/10.3389/fimmu.2022.896353

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