Multimericity Amplifies the Synergy of BCR and TLR4 for B Cell Activation and Antibody Class Switching

Sustained signaling through the B cell antigen receptor (BCR) is thought to occur only when antigen(s) crosslink or disperse multiple BCR units, such as by multimeric antigens found on the surfaces of viruses or bacteria. B cell-intrinsic Toll-like receptor (TLR) signaling synergizes with the BCR to...

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Detalles Bibliográficos
Autores principales: Pone, Egest J., Hernandez-Davies, Jenny E., Jan, Sharon, Silzel, Emily, Felgner, Philip L., Davies, D. Huw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161726/
https://www.ncbi.nlm.nih.gov/pubmed/35663959
http://dx.doi.org/10.3389/fimmu.2022.882502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161726/
https://www.ncbi.nlm.nih.gov/pubmed/35663959
http://dx.doi.org/10.3389/fimmu.2022.882502

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