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Multimericity Amplifies the Synergy of BCR and TLR4 for B Cell Activation and Antibody Class Switching
Sustained signaling through the B cell antigen receptor (BCR) is thought to occur only when antigen(s) crosslink or disperse multiple BCR units, such as by multimeric antigens found on the surfaces of viruses or bacteria. B cell-intrinsic Toll-like receptor (TLR) signaling synergizes with the BCR to...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161726/ https://www.ncbi.nlm.nih.gov/pubmed/35663959 http://dx.doi.org/10.3389/fimmu.2022.882502 |