Cargando…

Targeting Forkhead box O1-aquaporin 5 axis mitigates neuropathic pain in a CCI rat model through inhibiting astrocytic and microglial activation

Forkhead box O1 (FoxO1) is a critical molecule in modulating cell growth, differentiation and metabolism, acting as a vital transcription factor. This study explored the role of FoxO1 in chronic constriction injury (CCI)-induced neuropathic pain (NP). Microglial and astrocyte activation was achieved...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Yaoping, Wang, Meng, Yu, Xiao, Yan, Yi, Yu, Bo, Zhang, Dayin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161847/
https://www.ncbi.nlm.nih.gov/pubmed/35324416
http://dx.doi.org/10.1080/21655979.2022.2053032