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Role of sirtuin 1 in the brain development in congenital hypothyroidism rats via the regulation of p53 signaling pathway
The present study aimed to investigate the expression, role, and underlying mechanism of action of sirtuin 1 (SIRT1) in congenital hypothyroidism (CH). A CH model was established in rats, and neuronal cells were isolated from the hippocampal tissues of normal rats. Free thyroxine (fT4) and thyroid-S...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161855/ https://www.ncbi.nlm.nih.gov/pubmed/35383535 http://dx.doi.org/10.1080/21655979.2022.2060626 |