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Knockdown of lectin-like oxidized low-density lipoprotein-1 ameliorates alcoholic cardiomyopathy via inactivating the p38 mitogen-activated protein kinase pathway

LOX-1 triggers myocardial fibrosis, but its roles and mechanisms in alcoholic cardiomyopathy and the involvement of the downstream signaling pathways had not been fully reported. We planned to explore how LOX-1 facilitated myocardial fibrosis in alcoholic cardiomyopathy. The in vitro and in vivo alc...

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Detalles Bibliográficos
Autores principales: Zhang, Yifan, Zhang, Ruiqi, Lu, Lan, Zhou, Na, Lv, Xiaoyan, Wang, Xin, Feng, Zhanbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161863/
https://www.ncbi.nlm.nih.gov/pubmed/35333694
http://dx.doi.org/10.1080/21655979.2022.2056814