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Exosomes from human adipose-derived mesenchymal stem cells inhibit production of extracellular matrix in keloid fibroblasts via downregulating transforming growth factor-β2 and Notch-1 expression

Keloids are an excessive tissue response to dermal damage, characterized by uncontrolled growth and a high recurrence rate after various treatments. Abnormalities with the extracellular matrix (ECM) are one of the most important contributing factors to the formation of keloids. Although exosomes fro...

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Detalles Bibliográficos
Autores principales: Li, Jing, Li, Zhiyu, Wang, Song, Bi, Jianhai, Huo, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161879/
https://www.ncbi.nlm.nih.gov/pubmed/35333672
http://dx.doi.org/10.1080/21655979.2022.2051838