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Uterus globulin associated protein 1 (UGRP1) binds podoplanin (PDPN) to promote a novel inflammation pathway during Streptococcus pneumoniae infection

BACKGROUND: Streptococcus pneumoniae is the major cause of life‐threatening infections. Toll‐like receptors (TLRs) and NOD‐like receptors (NLRs) could recognise S. pneumoniae and regulate the production of pro‐inflammatory cytokines. UGRP1, highly expressed in lung, is predominantly secreted in airw...

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Detalles Bibliográficos
Autores principales: Han, Lei, Zhang, Feifei, Liu, Yu, Yu, Jie, Zhang, Qianyue, Ye, Xiaoping, Song, Huaidong, Zheng, Cuixia, Han, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161880/
https://www.ncbi.nlm.nih.gov/pubmed/35652821
http://dx.doi.org/10.1002/ctm2.850