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Overexpression of OTU domain-containing ubiquitin aldehyde-binding protein 1 exacerbates colorectal cancer malignancy by inhibiting protein degradation of β-Catenin via Ubiquitin-proteasome pathway

Although major advances were achieved in colorectal cancer (CRC) therapy, major concerns still remain on proper control of cancer metastasis and chemo-resistance in order to achieve satisfactory general treatment response. Previous studies suggested that OTUB1 (OTU domain-containing ubiquitin aldehy...

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Detalles Bibliográficos
Autores principales: Ye, Daoxiong, Wang, Sisi, Wang, Xiaojie, Lin, Yu, Huang, Ying, Chi, Pan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161894/
https://www.ncbi.nlm.nih.gov/pubmed/35354355
http://dx.doi.org/10.1080/21655979.2022.2057897