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Protecting effect of emodin in experimental autoimmune encephalomyelitis mice by inhibiting microglia activation and inflammation via Myd88/PI3K/Akt/NF-κB signalling pathway

Experimental autoimmune encephalomyelitis (EAE) is characterized by demyelination of the central nervous system. Emodin is an anthraquinone derivative with comprehensive anti-inflammatory, anti-cancer, and immunomodulatory effects and is widely used in the treatment of inflammatory, tumor, and immun...

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Detalles Bibliográficos
Autores principales: Zheng, Kenan, Lv, Baojiang, Wu, Lulu, Wang, Chen, Xu, Haoyou, Li, Xiaojun, Wu, Zhibing, Zhao, Yuanqi, Zheng, Zequan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161934/
https://www.ncbi.nlm.nih.gov/pubmed/35287559
http://dx.doi.org/10.1080/21655979.2022.2052671