Cargando…

Oxycodone protects cardiac microvascular endothelial cells against ischemia/reperfusion injury by binding to Sigma-1 Receptor

Endothelial dysfunction is an important mechanism involved in myocardial ischemia-reperfusion (I/R) injury. We aimed to explore the effects of Oxycodone on myocardial I/R injury in vivo and in vitro to reveal its mechanisms related to Sigma-1 Receptor (SIGMAR1). A rat model of I/R-induced myocardial...

Descripción completa

Detalles Bibliográficos
Autores principales: Ji, Meihua, Cheng, Jing, Zhang, Daimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161947/
https://www.ncbi.nlm.nih.gov/pubmed/35412431
http://dx.doi.org/10.1080/21655979.2022.2057632