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Downregulation of fatty acid binding protein 4 alleviates lipid peroxidation and oxidative stress in diabetic retinopathy by regulating peroxisome proliferator-activated receptor γ-mediated ferroptosis

This study aims to explore the role of fatty acid binding protein 4 (FABP4) in diabetic retinopathy (DR), and to elucidate the potential regulatory mechanism. We firstly developed a mouse model of DR by injection with streptozocin (STZ) into C57BL/6 male mice and a cell model of DR by induction of h...

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Detalles Bibliográficos
Autores principales: Fan, Xiao’e, Xu, Manhong, Ren, Qianfeng, Fan, Yan, Liu, Boshi, Chen, Jiaqi, Wang, Zhengmin, Sun, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9161966/
https://www.ncbi.nlm.nih.gov/pubmed/35441580
http://dx.doi.org/10.1080/21655979.2022.2062533