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Astragaloside-IV alleviates high glucose-induced ferroptosis in retinal pigment epithelial cells by disrupting the expression of miR-138-5p/Sirt1/Nrf2

Astragaloside-IV (AS-IV) (C(41)H(68)O(14)) is a high-purity natural product extracted from Astragalus, which has demonstrated biological activities. However, the effect of AS-IV on retinal pigment epithelial (RPE) cells in diabetic retinopathy (DR) remains unclear. In this study, high glucose (HG) w...

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Detalles Bibliográficos
Autores principales: Tang, Xuyuan, Li, Xiuyi, Zhang, Dongyan, Han, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162003/
https://www.ncbi.nlm.nih.gov/pubmed/35302431
http://dx.doi.org/10.1080/21655979.2022.2049471