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Calcium-binding protein 39 overexpression promotes macrophages from ‘M1’ into ‘M2’ phenotype and improves chondrocyte damage in osteoarthritis by activating the AMP-activated protein kinase/sirtuin 1 axis

Osteoarthritis (OA) is a degenerative joint disease that affects cartilage and its peripheral tissues. Up-regulation of Calcium-binding protein 39 (CAB39) has a significant protective effect on osteoblasts, but the role and related molecular mechanisms of CAB39 in OA have not yet been reported. CAB3...

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Detalles Bibliográficos
Autores principales: Liu, Qiuliang, Pian, Kai, Tian, Zhen, Duan, Haitao, Wang, Qi, Zhang, Hui, Shi, Longyan, Song, Dongjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162023/
https://www.ncbi.nlm.nih.gov/pubmed/35412939
http://dx.doi.org/10.1080/21655979.2022.2061289