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Calcium-binding protein 39 overexpression promotes macrophages from ‘M1’ into ‘M2’ phenotype and improves chondrocyte damage in osteoarthritis by activating the AMP-activated protein kinase/sirtuin 1 axis
Osteoarthritis (OA) is a degenerative joint disease that affects cartilage and its peripheral tissues. Up-regulation of Calcium-binding protein 39 (CAB39) has a significant protective effect on osteoblasts, but the role and related molecular mechanisms of CAB39 in OA have not yet been reported. CAB3...
Autores principales: | Liu, Qiuliang, Pian, Kai, Tian, Zhen, Duan, Haitao, Wang, Qi, Zhang, Hui, Shi, Longyan, Song, Dongjian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162023/ https://www.ncbi.nlm.nih.gov/pubmed/35412939 http://dx.doi.org/10.1080/21655979.2022.2061289 |
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