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Sp1 transcription factor represses transcription of phosphatase and tensin homolog to aggravate lung injury in mice with type 2 diabetes mellitus-pulmonary tuberculosis

Type 2 diabetes mellitus (T2DM) can enhance the risk of mycobacterium tuberculosis (Mtb) infection and aggravate pulmonary tuberculosis (PTB). This study intended to explore the function of phosphatase and tensin homolog (PTEN) in T2DM-PTB and the molecules involved. Mice were treated with streptozo...

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Detalles Bibliográficos
Autores principales: Zhao, Hongmei, Shi, Lian, Wang, Xiaohong, Yu, Xiuli, Wang, Danfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162029/
https://www.ncbi.nlm.nih.gov/pubmed/35420971
http://dx.doi.org/10.1080/21655979.2022.2062196