Reduction of Drosophila Mitochondrial RNase P in Skeletal and Heart Muscle Causes Muscle Degeneration, Cardiomyopathy, and Heart Arrhythmia

In this study, we examine the cause and progression of mitochondrial diseases linked to the loss of mtRNase P, a three-protein complex responsible for processing and cleaving mitochondrial transfer RNAs (tRNA) from their nascent transcripts. When mtRNase P function is missing, mature mitochondrial t...

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Detalles Bibliográficos
Autores principales: Saoji, Maithili, Petersen, Courtney E., Sen, Aditya, Tripoli, Benjamin A., Smyth, Jeremy T., Cox, Rachel T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162060/
https://www.ncbi.nlm.nih.gov/pubmed/35663400
http://dx.doi.org/10.3389/fcell.2022.788516

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162060/
https://www.ncbi.nlm.nih.gov/pubmed/35663400
http://dx.doi.org/10.3389/fcell.2022.788516

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