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A multi-population phenome-wide association study of genetically-predicted height in the Million Veteran Program

BACKGROUND: Height has been associated with many clinical traits but whether such associations are causal versus secondary to confounding remains unclear in many cases. To systematically examine this question, we performed a Mendelian Randomization-Phenome-wide association study (MR-PheWAS) using cl...

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Detalles Bibliográficos
Autores principales: Raghavan, Sridharan, Huang, Jie, Tcheandjieu, Catherine, Huffman, Jennifer E., Litkowski, Elizabeth, Liu, Chang, Ho, Yuk-Lam A., Hunter-Zinck, Haley, Zhao, Hongyu, Marouli, Eirini, North, Kari E., Lange, Ethan, Lange, Leslie A., Voight, Benjamin F., Gaziano, J. Michael, Pyarajan, Saiju, Hauser, Elizabeth R., Tsao, Philip S., Wilson, Peter W. F., Chang, Kyong-Mi, Cho, Kelly, O’Donnell, Christopher J., Sun, Yan V., Assimes, Themistocles L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162317/
https://www.ncbi.nlm.nih.gov/pubmed/35653334
http://dx.doi.org/10.1371/journal.pgen.1010193