Diet-responsive transcriptional regulation of insulin in a single neuron controls systemic metabolism

Metabolic homeostasis is coordinated through a robust network of signaling pathways acting across all tissues. A key part of this network is insulin-like signaling, which is fundamental for surviving glucose stress. Here, we show that Caenorhabditis elegans fed excess dietary glucose reduce insulin-...

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Detalles Bibliográficos
Autores principales: Handley, Ava, Wu, Qiuli, Sherry, Tessa, Cornell, Rebecca, Pocock, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162364/
https://www.ncbi.nlm.nih.gov/pubmed/35594303
http://dx.doi.org/10.1371/journal.pbio.3001655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162364/
https://www.ncbi.nlm.nih.gov/pubmed/35594303
http://dx.doi.org/10.1371/journal.pbio.3001655

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