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Divergent binding mode for a protozoan BRC repeat to RAD51

Interaction of BRCA2 through ca. 30 amino acid residue motifs, BRC repeats, with RAD51 is a conserved feature of the double-strand DNA break repair by homologous recombination in eukaryotes. In humans the binding of the eight BRC repeats is defined by two sequence motifs, FxxA and LFDE, interacting...

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Detalles Bibliográficos
Autores principales: Pantelejevs, Teodors, Hyvönen, Marko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162458/
https://www.ncbi.nlm.nih.gov/pubmed/35502837
http://dx.doi.org/10.1042/BCJ20220141