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PIDD1 in cell cycle control, sterile inflammation and cell death

The death fold domain-containing protein PIDD1 has recently attracted renewed attention as a regulator of the orphan cell death-related protease, Caspase-2. Caspase-2 can activate p53 to promote cell cycle arrest in response to centrosome aberrations, and its activation requires formation of the PID...

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Detalles Bibliográficos
Autores principales: Weiler, Elias S., Szabo, Tamas G., Garcia-Carpio, Irmina, Villunger, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162469/
https://www.ncbi.nlm.nih.gov/pubmed/35343572
http://dx.doi.org/10.1042/BST20211186